PIC is an actively used text markup language created in 1988.

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Example code from Linguist:

# Dextroamphetamine molecule
.cstart
	.ps 26
	size 28
R1:
	ring double 1,2 3,4 5,6
	bond 60 from R1.V2
	bond 120
A1:
	front bond down ; CH3
	bond 60 from A1 ; NH2
	.ps
.cend
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Last updated February 11th, 2019